Comprehensive Analysis of Copy Number Variations in Kidney Cancer by Single-Cell Exome Sequencing

Clear-cell renal cell carcinoma (ccRCC) is the most common and lethal subtype of kidney cancer. VHL and PBRM1 are the top two significantly mutated genes in ccRCC specimens, while the genetic mechanism of the VHL/PBRM1-negative ccRCC remains to be elucidated. Here we carried out a comprehensive anal...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Zhou, Wenyang, Yang, Fan, Xu, Zhaochun, Luo, Meng, Wang, Pingping, Guo, Yu, Nie, Huan, Yao, Lifen, Jiang, Qinghua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989475/
https://ncbi.nlm.nih.gov/pubmed/32038722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01379
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