Comprehensive Analysis of Copy Number Variations in Kidney Cancer by Single-Cell Exome Sequencing

Clear-cell renal cell carcinoma (ccRCC) is the most common and lethal subtype of kidney cancer. VHL and PBRM1 are the top two significantly mutated genes in ccRCC specimens, while the genetic mechanism of the VHL/PBRM1-negative ccRCC remains to be elucidated. Here we carried out a comprehensive anal...

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Bibliografiska uppgifter
I publikationen:Front Genet
Huvudupphovsmän: Zhou, Wenyang, Yang, Fan, Xu, Zhaochun, Luo, Meng, Wang, Pingping, Guo, Yu, Nie, Huan, Yao, Lifen, Jiang, Qinghua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Genetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989475/
https://ncbi.nlm.nih.gov/pubmed/32038722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01379
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