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THE ROLE OF LTB(4)-BLT1 AXIS IN CHEMOTACTIC GRADIENT SENSING AND DIRECTED LEUKOCYTE MIGRATION

Directed leukocyte migration is a hallmark of inflammatory immune responses. Leukotrienes are derived from arachidonic acid and represent a class of potent lipid mediators of leukocyte migration. In this review, we summarize the essential steps leading to the production of LTB(4) in leukocytes. We d...

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Detalhes bibliográficos
Publicado no:Semin Immunol
Main Authors: Subramanian, Bhagawat C., Majumdar, Ritankar, Parent, Carole A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288505/
https://ncbi.nlm.nih.gov/pubmed/29042024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2017.07.002
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