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Reducing Auditory Nerve Excitability by Acute Antagonism of Ca(2+)-Permeable AMPA Receptors
Hearing depends on glutamatergic synaptic transmission mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). AMPARs are tetramers, where inclusion of the GluA2 subunit reduces overall channel conductance and Ca(2+) permeability. Cochlear afferent synapses between inner...
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| Publicado no: | Front Synaptic Neurosci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8287724/ https://ncbi.nlm.nih.gov/pubmed/34290596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2021.680621 |
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