Tumor rejection in Cblb(−/−) mice depends on IL-9 and Th9 cells

BACKGROUND: Casitas B lymphoma-b (Cbl-b) is a central negative regulator of cytotoxic T and natural killer (NK) cells and functions as an intracellular checkpoint in cancer. In particular, Th9 cells support mast cell activation, promote dendritic cell recruitment, enhance the cytolytic function of c...

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Bibliografische gegevens
Gepubliceerd in:J Immunother Cancer
Hoofdauteurs: Schanz, Oliver, Cornez, Isabelle, Yajnanarayana, Sowmya Parampalli, David, Friederike Sophie, Peer, Sebastian, Gruber, Thomas, Krawitz, Peter, Brossart, Peter, Heine, Annkristin, Landsberg, Jenny, Baier, Gottfried, Wolf, Dominik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2021
Onderwerpen:
Basic Tumor Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287598/
https://ncbi.nlm.nih.gov/pubmed/34272310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2021-002889
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