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Relationship between de novo lipogenesis and serum sex hormone binding globulin in humans

OBJECTIVE: Obesity and liver fat are associated with decreased levels of serum sex hormone binding globulin (SHBG). Laboratory studies suggest that hepatic de novo lipogenesis (DNL) is involved in the downregulation of SHBG synthesis. The aim of the present study was to address the role of DNL on se...

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Veröffentlicht in:Clin Endocrinol (Oxf)
Hauptverfasser: Simons, Pomme I. H. G., Valkenburg, Olivier, Telgenkamp, Ine, van der Waaij, Koen M., de Groot, David M., Veeraiah, Pandichelvam, Bons, Judith A. P., Taskinen, Marja‐Riitta, Borén, Jan, Schrauwen, Patrick, Rutten, Joost H. W., Cassiman, David, Schalkwijk, Casper G., Stehouwer, Coen D. A., Schrauwen‐Hinderling, Vera B., Hodson, Leanne, Brouwers, Martijn C. G. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287427/
https://ncbi.nlm.nih.gov/pubmed/33715205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cen.14459
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