Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Hepatic saturated fatty acids (SFA) may be a marker of DNL and are suggested to be most detrimental in contributing to insulin resista...

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Publicado no:Nat Commun
Main Authors: Roumans, Kay H. M., Lindeboom, Lucas, Veeraiah, Pandichelvam, Remie, Carlijn M. E., Phielix, Esther, Havekes, Bas, Bruls, Yvonne M. H., Brouwers, Martijn C. G. J., Ståhlman, Marcus, Alssema, Marjan, Peters, Harry P. F., de Mutsert, Renée, Staels, Bart, Taskinen, Marja-Riitta, Borén, Jan, Schrauwen, Patrick, Schrauwen-Hinderling, Vera B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170906/
https://ncbi.nlm.nih.gov/pubmed/32312974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15684-0
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