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Expression of Rab Prenylation Pathway Genes and Relation to Disease Progression in Choroideremia

PURPOSE: Choroideremia results from the deficiency of Rab Escort Protein 1 (REP1), encoded by CHM, involved in the prenylation of Rab GTPases. Here, we investigate whether the transcription and expression of other genes involved in the prenylation of Rab proteins correlates with disease progression...

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Detalhes bibliográficos
Publicado no:Transl Vis Sci Technol
Main Authors: Fry, Lewis E., Patrício, Maria I., Jolly, Jasleen K., Xue, Kanmin, MacLaren, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287038/
https://ncbi.nlm.nih.gov/pubmed/34254989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.10.8.12
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