Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

BACKGROUND: Abnormally elevated xanthine oxidase (XO) activity has been verified to cause various pathological processes, such as gout, oxidative stress injury and metabolic syndrome. Thus, XO activators may exhibit above potential toxicological properties. Plumbagin (PLB) is an important active com...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Pharmacol Toxicol
Auteurs principaux: Yue, Liang, Jiang, Nan, Wu, Anguo, Qiu, Wenqiao, Shen, Xin, Qin, Dalian, Li, Hong, Lin, Jing, Liang, Sicheng, Wu, Jianming
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286619/
https://ncbi.nlm.nih.gov/pubmed/34274011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00511-z
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