Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

BACKGROUND: Abnormally elevated xanthine oxidase (XO) activity has been verified to cause various pathological processes, such as gout, oxidative stress injury and metabolic syndrome. Thus, XO activators may exhibit above potential toxicological properties. Plumbagin (PLB) is an important active com...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Yue, Liang, Jiang, Nan, Wu, Anguo, Qiu, Wenqiao, Shen, Xin, Qin, Dalian, Li, Hong, Lin, Jing, Liang, Sicheng, Wu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286619/
https://ncbi.nlm.nih.gov/pubmed/34274011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-021-00511-z
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