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In silico design and synthesis of hesperitin derivatives as new xanthine oxidase inhibitors

BACKGROUND: Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with gout and many life style related disorders. O...

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Detalhes bibliográficos
Publicado no:BMC Chem
Main Authors: Malik, Neelam, Dhiman, Priyanka, Khatkar, Anurag
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661729/
https://ncbi.nlm.nih.gov/pubmed/31384801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0571-1
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