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Targeted Protein Degradation: A Promise for Undruggable Proteins
Protein homeostasis, or “proteostasis”, is indispensable for a balanced, healthy environment within the cell. However, when natural proteostasis mechanisms are overwhelmed from excessive loads of dysregulated proteins, their accumulation can lead to disease initiation and progression. Fortunately, t...
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| Udgivet i: | Cell Chem Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8286327/ https://ncbi.nlm.nih.gov/pubmed/34004187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2021.04.011 |
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