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DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65

Parkinson’s disease (PD), one of the most common neurodegenerative disorders, is characterized by progressive neurodegeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). DJ-1 acts essential roles in neuronal protection and anti-neuroinflammatory response, and its los...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Lin, Zixuan, Chen, Chen, Yang, Dongqin, Ding, Jianqing, Wang, Guanghui, Ren, Haigang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286256/
https://ncbi.nlm.nih.gov/pubmed/34274951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04002-1
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