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DJ-1 inhibits microglial activation and protects dopaminergic neurons in vitro and in vivo through interacting with microglial p65

Parkinson’s disease (PD), one of the most common neurodegenerative disorders, is characterized by progressive neurodegeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). DJ-1 acts essential roles in neuronal protection and anti-neuroinflammatory response, and its los...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lin, Zixuan, Chen, Chen, Yang, Dongqin, Ding, Jianqing, Wang, Guanghui, Ren, Haigang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8286256/
https://ncbi.nlm.nih.gov/pubmed/34274951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04002-1
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