P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease. Although its pathogenesis remains unclear, mitochondrial dysfunction plays a vital role in the pathology of PD. P7C3, an aminopropyl carbazole, possesses a significant neuroprotective ability in several neurodegenerativ...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gu, Chao, Zhang, Yan, Hu, Qingsong, Wu, Jiayuan, Ren, Haigang, Liu, Chun-Feng, Wang, Guanghui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520908/
https://ncbi.nlm.nih.gov/pubmed/28569794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.250
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