1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long–sought-after mimetics for ortho/meta-substituted arenes

The development of a versatile platform for the synthesis of 1,2-difunctionalized bicyclo[1.1.1]pentanes to potentially mimic ortho/meta-substituted arenes is described. The syntheses of useful building blocks bearing alcohol, amine, and carboxylic acid functional handles have been achieved from a s...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhao, Jin-Xin, Chang, Yu-Xuan, He, Chi, Burke, Benjamin J., Collins, Michael R., Del Bel, Matthew, Elleraas, Jeff, Gallego, Gary M., Montgomery, T. Patrick, Mousseau, James J., Nair, Sajiv K., Perry, Matthew A., Spangler, Jillian E., Vantourout, Julien C., Baran, Phil S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
Soggetti:
Physical Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285974/
https://ncbi.nlm.nih.gov/pubmed/34244445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2108881118
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