Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell–derived skeletal muscle in vitro

Duchenne muscular dystrophy (DMD) is a devastating genetic disease leading to degeneration of skeletal muscles and premature death. How dystrophin absence leads to muscle wasting remains unclear. Here, we describe an optimized protocol to differentiate human induced pluripotent stem cells (iPSC) to...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Al Tanoury, Ziad, Zimmerman, John F., Rao, Jyoti, Sieiro, Daniel, McNamara, Harold M., Cherrier, Thomas, Rodríguez-delaRosa, Alejandra, Hick-Colin, Aurore, Bousson, Fanny, Fugier-Schmucker, Charlotte, Marchiano, Fabio, Habermann, Bianca, Chal, Jérome, Nesmith, Alexander P., Gapon, Svetlana, Wagner, Erica, Gupta, Vandana A., Bassel-Duby, Rhonda, Olson, Eric N., Cohen, Adam E., Parker, Kevin Kit, Pourquié, Olivier
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285911/
https://ncbi.nlm.nih.gov/pubmed/34260377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022960118
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