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Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism

Leucine-rich repeat-containing 8 (LRRC8) volume-regulated anion channels (VRACs) play important physiological roles in diverse cell types and may represent therapeutic targets for various diseases. To date, however, the pharmacological tools for evaluating the druggability of VRACs have been limited...

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Bibliografske podrobnosti
izdano v:Am J Physiol Cell Physiol
Main Authors: Figueroa, Eric E., Denton, Jerod S.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285639/
https://ncbi.nlm.nih.gov/pubmed/33826406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00070.2021
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