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Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism
Leucine-rich repeat-containing 8 (LRRC8) volume-regulated anion channels (VRACs) play important physiological roles in diverse cell types and may represent therapeutic targets for various diseases. To date, however, the pharmacological tools for evaluating the druggability of VRACs have been limited...
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| Publicado no: | Am J Physiol Cell Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8285639/ https://ncbi.nlm.nih.gov/pubmed/33826406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00070.2021 |
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