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Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis

Senescent vascular cells are detected in atherosclerotic lesion, and its involvement in the development of atherosclerosis has been revealed; however, whether and the mechanism by which endothelial cell (EC) senescence is causally implicated in atherosclerosis remains unclear. We here investigate a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Honda, Sakiko, Ikeda, Koji, Urata, Ryota, Yamazaki, Ekura, Emoto, Noriaki, Matoba, Satoaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285500/
https://ncbi.nlm.nih.gov/pubmed/34272458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94097-5
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