Pinocembrin attenuates hemorrhagic transformation after delayed t-PA treatment in thromboembolic stroke rats by regulating endogenous metabolites

Hemorrhagic transformation (HT) is a common serious complication of stroke after thrombolysis treatment, which limits the clinical use of tissue plasminogen activator (t-PA). Since early diagnosis and treatment for HT is important to improve the prognosis of stroke patients, it is urgent to discover...

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Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Kong, Ling-lei, Gao, Li, Wang, Ke-xin, Liu, Nan-nan, Liu, Cheng-di, Ma, Guo-dong, Yang, Hai-guang, Qin, Xue-mei, Du, Guan-hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Singapore 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285418/
https://ncbi.nlm.nih.gov/pubmed/33859344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-021-00664-x
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