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Inhibition of Nav1.7 channel by a novel blocker QLS-81 for alleviation of neuropathic pain
Voltage-gated sodium channel Nav1.7 robustly expressed in peripheral nociceptive neurons has been considered as a therapeutic target for chronic pain, but there is no selective Nav1.7 inhibitor available for therapy of chronic pain. Ralfinamide has shown anti-nociceptive activity in animal models of...
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| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8285378/ https://ncbi.nlm.nih.gov/pubmed/34103689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-021-00682-9 |
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