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Probing the Interaction of Huntingtin Exon-1 Polypeptides with the Chaperonin Nanomachine GroEL
Huntington’s disease arises from polyQ expansion within the exon-1 region of huntingtin (htt(ex1)), resulting in an aggregation prone protein that accumulates in neuronal inclusion bodies. We investigate the interaction of various htt(ex1) constructs with the bacterial analog (GroEL) of the human ch...
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| 出版年: | Chembiochem |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284913/ https://ncbi.nlm.nih.gov/pubmed/33644966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202100055 |
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