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Plasmid hypermutation using a targeted artificial DNA replisome
Extensive exploration of a protein’s sequence space for improved or new molecular functions requires in vivo evolution with large populations. But disentangling the evolution of a target protein from the rest of the proteome is challenging. Here, we designed a protein complex of a targeted artificia...
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| Publicado en: | Sci Adv |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284885/ https://ncbi.nlm.nih.gov/pubmed/34272238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg8712 |
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