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Uncoupling Sonic Hedgehog Control of Pattern and Expansion of the Developing Limb Bud
Sonic hedgehog (Shh), which regulates proliferation in many contexts, functions as a limb morphogen to specify a distinct pattern of digits. How Shh’s effects on cell number relate to its role in specifying digit identity is unclear. Deleting the mouse Shh gene at different times using a conditional...
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| Publicado en: | Dev Cell |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284562/ https://ncbi.nlm.nih.gov/pubmed/18410737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.01.008 |
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