Acquisition of Tigecycline Resistance by Carbapenem-Resistant Klebsiella pneumoniae Confers Collateral Hypersensitivity to Aminoglycosides

Tigecycline is a last-resort antibiotic for infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP). This study aimed to broaden our understanding of the acquisition of collateral hypersensitivity by CRKP, as an evolutionary trade-off of developing resistance to tigecycline. Experimen...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Chen, Hua-le, Jiang, Yan, Li, Mei-mei, Sun, Yao, Cao, Jian-ming, Zhou, Cui, Zhang, Xiao-xiao, Qu, Yue, Zhou, Tie-li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284424/
https://ncbi.nlm.nih.gov/pubmed/34276606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.674502
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