Roles of ramR and tet(A) Mutations in Conferring Tigecycline Resistance in Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates

Tigecycline is regarded as a last-resort treatment for carbapenem-resistant Klebsiella pneumoniae (CRKP) infections, but increasing numbers of tigecycline-resistant K. pneumoniae isolates have been reported. The tigecycline resistance mechanisms in CRKP are undetermined. This study aimed to elucidat...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Chiu, Sheng-Kang, Huang, Li-Yueh, Chen, Hsi, Tsai, Yu-Kuo, Liou, Ci-Hong, Lin, Jung-Chung, Siu, L. Kristopher, Chang, Feng-Yee, Yeh, Kuo-Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Mechanisms of Resistance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527587/
https://ncbi.nlm.nih.gov/pubmed/28533243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00391-17
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