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Evidence for ligandable sites in structured RNA throughout the Protein Data Bank

RNA has attracted considerable attention as a target for small molecules. However, methods to identify, study, and characterize suitable RNA targets have lagged behind strategies for protein targets. One approach that has received considerable attention for protein targets has been to utilize comput...

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Vydáno v:Bioorg Med Chem
Hlavní autoři: Hewitt, William M., Calabrese, David R., Schneekloth, John S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283815/
https://ncbi.nlm.nih.gov/pubmed/30982658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.04.010
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