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A stress-free strategy to correct point mutations in patient iPS cells

When studying patient specific induced pluripotent stem cells (iPS cells) as a disease model, the ideal control is an isogenic line that has corrected the point mutation, instead of iPS cells from siblings or other healthy subjects. However, repairing a point mutation in iPS cells even with the newl...

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: Cai, Jingli, Kropf, Elizabeth, Hou, Ya-Ming, Iacovitti, Lorraine
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283763/
https://ncbi.nlm.nih.gov/pubmed/33857832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2021.102332
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