DPYD, down-regulated by the potentially chemopreventive agent luteolin, interacts with STAT3 in pancreatic cancer

The 5-year survival rate of pancreatic ductal carcinoma (PDAC) patients is <10% despite progress in clinical medicine. Strategies to prevent the development of PDAC are urgently required. The flavonoids Luteolin (Lut) and hesperetin (Hes) may be cancer-chemopreventive, but effects on pancreatic c...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Carcinogenesis
Hauptverfasser: Kato, Hiroyuki, Naiki-Ito, Aya, Suzuki, Shugo, Inaguma, Shingo, Komura, Masayuki, Nakao, Kenju, Naiki, Taku, Kachi, Kenta, Kato, Akihisa, Matsuo, Yoichi, Takahashi, Satoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Inflammation, Microenvironment and Prevention
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283735/
https://ncbi.nlm.nih.gov/pubmed/33640964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgab017
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