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Pre-Clinical Compartmental Pharmacokinetic Modeling of 2-[1-hexyloxyethyl]-2-Devinyl Pyropheophorbide-a (HPPH) as a Photosensitizer in Rat Plasma by Validated HPLC Method
A second-generation chlorin-based photosensitizer, 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) has shown tremendous therapeutic potential in clinical trials in the treatment of esophageal cancer. Herein, we have developed and validated a bioanalytical method for estimation of HPPH in rat...
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| Veröffentlicht in: | Photochem Photobiol Sci |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8283519/ https://ncbi.nlm.nih.gov/pubmed/30608096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8pp00339d |
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