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Pre-Clinical Compartmental Pharmacokinetic Modeling of 2-[1-hexyloxyethyl]-2-Devinyl Pyropheophorbide-a (HPPH) as a Photosensitizer in Rat Plasma by Validated HPLC Method

A second-generation chlorin-based photosensitizer, 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a (HPPH) has shown tremendous therapeutic potential in clinical trials in the treatment of esophageal cancer. Herein, we have developed and validated a bioanalytical method for estimation of HPPH in rat...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Photochem Photobiol Sci
Päätekijät: Venkata Krishna, Kowthavarapu, Narayana Saha, Ranendra, Puri, Anu, Viard, Mathias, Shapiro, Bruce A., Kumar Dubey, Sunil
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283519/
https://ncbi.nlm.nih.gov/pubmed/30608096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8pp00339d
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