Superiority of Formalin-Fixed Paraffin-Embedded Brain Tissue for in vitro Assessment of Progressive Supranuclear Palsy Tau Pathology With [(18)F]PI-2620

Objectives: Autoradiography on brain tissue is used to validate binding targets of newly discovered radiotracers. The purpose of this study was to correlate quantification of autoradiography signal using the novel next-generation tau positron emission tomography (PET) radiotracer [(18)F]PI-2620 with...

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Detalles Bibliográficos
Publicado en:Front Neurol
Main Authors: Willroider, Marie, Roeber, Sigrun, Horn, Anja K. E., Arzberger, Thomas, Scheifele, Maximilian, Respondek, Gesine, Sabri, Osama, Barthel, Henryk, Patt, Marianne, Mishchenko, Olena, Schildan, Andreas, Mueller, André, Koglin, Norman, Stephens, Andrew, Levin, Johannes, Höglinger, Günter U., Bartenstein, Peter, Herms, Jochen, Brendel, Matthias, Beyer, Leonie
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Neurology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282895/
https://ncbi.nlm.nih.gov/pubmed/34276540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.684523
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