Assessment of (18)F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy

IMPORTANCE: Progressive supranuclear palsy (PSP) is a 4-repeat tauopathy. Region-specific tau aggregates establish the neuropathologic diagnosis of definite PSP post mortem. Future interventional trials against tau in PSP would strongly benefit from biomarkers that support diagnosis. OBJECTIVE: To i...

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Publicat a:JAMA Neurol
Autors principals: Brendel, Matthias, Barthel, Henryk, van Eimeren, Thilo, Marek, Ken, Beyer, Leonie, Song, Mengmeng, Palleis, Carla, Gehmeyr, Mona, Fietzek, Urban, Respondek, Gesine, Sauerbeck, Julia, Nitschmann, Alexander, Zach, Christian, Hammes, Jochen, Barbe, Michael T., Onur, Oezguer, Jessen, Frank, Saur, Dorothee, Schroeter, Matthias L., Rumpf, Jost-Julian, Rullmann, Michael, Schildan, Andreas, Patt, Marianne, Neumaier, Bernd, Barret, Olivier, Madonia, Jennifer, Russell, David S., Stephens, Andrew, Roeber, Sigrun, Herms, Jochen, Bötzel, Kai, Classen, Joseph, Bartenstein, Peter, Villemagne, Victor, Levin, Johannes, Höglinger, Günter U., Drzezga, Alexander, Seibyl, John, Sabri, Osama
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2020
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7341407/
https://ncbi.nlm.nih.gov/pubmed/33165511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2020.2526
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