Differential usage of transcriptional repressor Zeb2 enhancers, distinguishes adult and embryonic hematopoiesis.

The transcriptional repressor ZEB2 regulates development of many cell fates among somatic, neural and hematopoietic lineages, but the basis for its requirement in these diverse lineages is unclear. Here, we identified a 400 basepair (bp) region located 165 kilobases (kb) upstream of the Zeb2 transcr...

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Publicado no:Immunity
Main Authors: Huang, Xiao, Ferris, Stephen T., Kim, Sunkyung, Choudhary, Mayank N. K., Belk, Julia A., Fan, Changxu, Qi, Yanyan, Sudan, Raki, Xia, Yu, Desai, Pritesh, Chen, Jing, Ly, Nghi, Shi, Quanming, Bagadia, Prachi, Liu, Tiantian, Guilliams, Martin, Egawa, Takeshi, Colonna, Marco, Diamond, Michael S., Murphy, Theresa L., Satpathy, Ansuman T., Wang, Ting, Murphy, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282756/
https://ncbi.nlm.nih.gov/pubmed/34004142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2021.04.015
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