Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

PURPOSE: Invasive mucinous adenocarcinoma (IMA) is a unique subtype of lung adenocarcinoma, characterized genomically by frequent KRAS mutations or specific gene fusions, most commonly involving NRG1. Comprehensive analysis of a large series of IMAs utilizing broad DNA and RNA sequencing methods is...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Chang, Jason C., Offin, Michael, Falcon, Christina, Brown, David, Houck-Loomis, Brian R., Meng, Fanli, Rudneva, Vasilisa A., Won, Helen H., Amir, Sharon, Montecalvo, Joseph, Desmeules, Patrice, Kadota, Kyuichi, Adusumilli, Prasad S., Rusch, Valerie W., Teed, Sarah, Sabari, Joshua K., Benayed, Ryma, Nafa, Khedoudja, Borsu, Laetitia, Li, Bob T., Schram, Alison M., Arcila, Maria E., Travis, William D., Ladanyi, Marc, Drilon, Alexander, Rekhtman, Natasha
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282731/
https://ncbi.nlm.nih.gov/pubmed/33947695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-21-0423
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