Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain–gut–microbiota axis via the subdiaphragmatic vagus nerve

BACKGROUND: The brain–gut–microbiota axis plays a crucial role in the bidirectional interactions between the brain and the gut. Soluble epoxide hydrolase (coded by the Ephx2 gene) plays an important role in inflammation, which has been implicated in stress-related depression. Ephx2 knock-out (KO) mi...

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Detalhes bibliográficos
Publicado no:J Affect Disord
Main Authors: Wang, Siming, Ishima, Tamaki, Qu, Youge, Shan, Jiajing, Chang, Lijia, Wei, Yan, Zhang, Jiancheng, Pu, Yaoyu, Fujita, Yuko, Tan, Yunfei, Wang, Xingming, Ma, Li, Wan, Xiayun, Hammock, Bruce D., Hashimoto, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282729/
https://ncbi.nlm.nih.gov/pubmed/34147969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2021.06.006
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