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Zinc binding alters the conformational dynamics and drives the transport cycle of the cation diffusion facilitator YiiP
YiiP is a secondary transporter that couples Zn(2+) transport to the proton motive force. Structural studies of YiiP from prokaryotes and Znt8 from humans have revealed three different Zn(2+) sites and a conserved homodimeric architecture. These structures define the inward-facing and outward-facing...
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| Publié dans: | J Gen Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Rockefeller University Press
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8282283/ https://ncbi.nlm.nih.gov/pubmed/34254979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202112873 |
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