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Structural basis for the alternating access mechanism of the cation diffusion facilitator YiiP

YiiP is a dimeric antiporter from the cation diffusion facilitator family that uses the proton motive force to transport Zn(2+) across bacterial membranes. Previous work defined the atomic structure of an outward-facing conformation, the location of several Zn(2+) binding sites, and hydrophobic resi...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lopez-Redondo, Maria Luisa, Coudray, Nicolas, Zhang, Zhening, Alexopoulos, John, Stokes, David L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866550/
https://ncbi.nlm.nih.gov/pubmed/29507252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715051115
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