Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation

Pelizaeus-Merzbacher disease (PMD) is an X-linked leukodystrophy caused by mutations in Proteolipid Protein 1 (PLP1), encoding a major myelin protein, resulting in profound developmental delay and early lethality. Previous work showed involvement of unfolded protein response (UPR) and endoplasmic re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Stem Cell
Egile Nagusiak: Nobuta, Hiroko, Yang, Nan, Ng, Yi Han, Marro, Samuele G., Sabeur, Khalida, Chavali, Manideep, Stockley, John H., Killilea, David W., Walter, Patrick B., Zhao, Chao, Huie, Philip, Goldman, Steven A., Kriegstein, Arnold R., Franklin, Robin J.M., Rowitch, David H., Wernig, Marius
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282124/
https://ncbi.nlm.nih.gov/pubmed/31585094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.09.003
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