Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters

Successful development of a chemoprophylaxis against SARS-CoV-2 could provide a tool for infection prevention implementable alongside vaccination programmes. Camostat and nafamostat are serine protease inhibitors that inhibit SARS-CoV-2 viral entry in vitro but have not been characterised for chemop...

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Udgivet i:bioRxiv
Main Authors: Neary, M, Box, H, Sharp, J, Tatham, L, Curley, P, Herriott, J, Kijak, E, Arshad, U, Hobson, JJ, Rajoli, RKR, Pertinez, H, Valentijn, A, Dhaliwal, K, McCaughan, F, Rannard, SP, Kipar, A, Stewart, JP, Owen, A
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282100/
https://ncbi.nlm.nih.gov/pubmed/34268511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.07.08.451654
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