Dose prediction for repurposing nitazoxanide in SARS‐CoV‐2 treatment or chemoprophylaxis

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been declared a global pandemic and urgent treatment and prevention strategies are needed. Nitazoxanide, an anthelmintic drug, has been shown to exhibit in vitro activity against SARS‐CoV‐2. The present study used physiolog...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Rajoli, Rajith K. R., Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steven P., Aljayyoussi, Ghaith, Pennington, Shaun H., Hill, Andrew, Boffito, Marta, Ward, Steve A., Khoo, Saye H., Bray, Patrick G., O'Neill, Paul M., Hong, W. David, Biagini, Giancarlo A., Owen, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056737/
https://ncbi.nlm.nih.gov/pubmed/33085781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14619
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