Dose prediction for repurposing nitazoxanide in SARS‐CoV‐2 treatment or chemoprophylaxis

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been declared a global pandemic and urgent treatment and prevention strategies are needed. Nitazoxanide, an anthelmintic drug, has been shown to exhibit in vitro activity against SARS‐CoV‐2. The present study used physiolog...

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Publicat a:Br J Clin Pharmacol
Autors principals: Rajoli, Rajith K. R., Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steven P., Aljayyoussi, Ghaith, Pennington, Shaun H., Hill, Andrew, Boffito, Marta, Ward, Steve A., Khoo, Saye H., Bray, Patrick G., O'Neill, Paul M., Hong, W. David, Biagini, Giancarlo A., Owen, Andrew
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8056737/
https://ncbi.nlm.nih.gov/pubmed/33085781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14619
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