The Mitochondrial PHB Complex Determines Lipid Composition and Interacts With the Endoplasmic Reticulum to Regulate Ageing

Metabolic disorders are frequently associated with physiological changes that occur during ageing. The mitochondrial prohibitin complex (PHB) is an evolutionary conserved context-dependent modulator of longevity, which has been linked to alterations in lipid metabolism but which biochemical function...

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Udgivet i:Front Physiol
Main Authors: Lourenço, Artur B., Rodríguez-Palero, María Jesús, Doherty, Mary K., Cabrerizo Granados, David, Hernando-Rodríguez, Blanca, Salas, Joaquín J., Venegas-Calerón, Mónica, Whitfield, Phillip D., Artal-Sanz, Marta
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281979/
https://ncbi.nlm.nih.gov/pubmed/34276415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.696275
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