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The Mitochondrial PHB Complex Determines Lipid Composition and Interacts With the Endoplasmic Reticulum to Regulate Ageing

Metabolic disorders are frequently associated with physiological changes that occur during ageing. The mitochondrial prohibitin complex (PHB) is an evolutionary conserved context-dependent modulator of longevity, which has been linked to alterations in lipid metabolism but which biochemical function...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Lourenço, Artur B., Rodríguez-Palero, María Jesús, Doherty, Mary K., Cabrerizo Granados, David, Hernando-Rodríguez, Blanca, Salas, Joaquín J., Venegas-Calerón, Mónica, Whitfield, Phillip D., Artal-Sanz, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281979/
https://ncbi.nlm.nih.gov/pubmed/34276415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.696275
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