Downregulation of FeSOD-A expression in Leishmania infantum alters trivalent antimony and miltefosine susceptibility

BACKGROUND: Superoxide dismutase (SOD), a central component of the antioxidant defence system of most organisms, removes excess superoxide anions by converting them to oxygen and hydrogen peroxide. As iron (Fe) SOD is absent in the human host, this enzyme is a promising molecular target for drug dev...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Parasit Vectors
Egile Nagusiak: Santi, Ana Maria Murta, Silva, Paula Alves, Santos, Isabella Fernandes Martins, Murta, Silvane Maria Fonseca
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Short Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281622/
https://ncbi.nlm.nih.gov/pubmed/34266485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-021-04838-8
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