Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

Down syndrome (DS) is the most common genetic cause of Alzheimer’s disease (AD) due to trisomy for all or part of human chromosome 21 (Hsa21). It is also associated with other phenotypes including distinctive facial features, cardiac defects, growth delay, intellectual disability, immune system abno...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Chen, Xu-Qiao, Xing, Zhuo, Chen, Quang-Di, Salvi, Richard J., Zhang, Xuming, Tycko, Benjamin, Mobley, William C., Yu, Y. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281234/
https://ncbi.nlm.nih.gov/pubmed/34276349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.700280
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