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HILIC–MRM–MS for Linkage-Specific Separation of Sialylated Glycopeptides to Quantify Prostate-Specific Antigen Proteoforms

[Image: see text] Elevated serum prostate-specific antigen (PSA) levels in body fluids may indicate prostate cancer (PCa), but it is noted that the clinical performance is rather poor. Specificity and sensitivity values of 20 and 94% at a cutoff value of 4.1 ng/mL, respectively, result in overdiagno...

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Dettagli Bibliografici
Pubblicato in:J Proteome Res
Autori principali: van der Burgt, Yuri E. M., Siliakus, Kasper M., Cobbaert, Christa M., Ruhaak, L. Renee
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280738/
https://ncbi.nlm.nih.gov/pubmed/32142289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00050
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