HILIC–MRM–MS for Linkage-Specific Separation of Sialylated Glycopeptides to Quantify Prostate-Specific Antigen Proteoforms

[Image: see text] Elevated serum prostate-specific antigen (PSA) levels in body fluids may indicate prostate cancer (PCa), but it is noted that the clinical performance is rather poor. Specificity and sensitivity values of 20 and 94% at a cutoff value of 4.1 ng/mL, respectively, result in overdiagno...

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Bibliographic Details
Published in:J Proteome Res
Main Authors: van der Burgt, Yuri E. M., Siliakus, Kasper M., Cobbaert, Christa M., Ruhaak, L. Renee
Format: Artigo
Language:Inglês
Published: American Chemical Society 2020
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280738/
https://ncbi.nlm.nih.gov/pubmed/32142289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00050
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