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Dummy Atoms in Alchemical Free Energy Calculations

[Image: see text] In calculations of relative free energy differences, the number of atoms of the initial and final states is rarely the same. This necessitates the introduction of dummy atoms. These placeholders interact with the physical system only by bonded energy terms. We investigate the condi...

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Bibliographic Details
Published in:J Chem Theory Comput
Main Authors: Fleck, Markus, Wieder, Marcus, Boresch, Stefan
Format: Artigo
Language:Inglês
Published: American Chemical Society 2021
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280730/
https://ncbi.nlm.nih.gov/pubmed/34125525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c01328
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