Helicobacter pylori-Induced TLR9 Activation and Injury Are Associated With the Virulence-Associated Adhesin HopQ

Helicobacter pylori is the strongest risk factor for gastric adenocarcinoma. The H. pylori cancer-associated cag pathogenicity island (cag-PAI) encodes a type IV secretion system (T4SS), which translocates microbial DNA and activates TLR9; however, most cag-PAI(+)–infected persons do not develop can...

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Vydáno v:J Infect Dis
Hlavní autoři: Dooyema, Samuel D R, Krishna, Uma S, Loh, John T, Suarez, Giovanni, Cover, Timothy L, Peek, Richard M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280490/
https://ncbi.nlm.nih.gov/pubmed/33245103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa730
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