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Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events, transient protein sequestration and inter-organelle interactions. However, the role LDs play in antiviral innate immune pathways remains unknown. Here we demonstrate that induction of LDs occurs as early as...

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Vydáno v:Nat Commun
Hlavní autoři: Monson, E. A., Crosse, K. M., Duan, M., Chen, W., O’Shea, R. D., Wakim, L. M., Carr, J. M., Whelan, D. R., Helbig, K. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280141/
https://ncbi.nlm.nih.gov/pubmed/34262037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24632-5
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