Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events, transient protein sequestration and inter-organelle interactions. However, the role LDs play in antiviral innate immune pathways remains unknown. Here we demonstrate that induction of LDs occurs as early as...

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Publicado no:Nat Commun
Main Authors: Monson, E. A., Crosse, K. M., Duan, M., Chen, W., O’Shea, R. D., Wakim, L. M., Carr, J. M., Whelan, D. R., Helbig, K. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280141/
https://ncbi.nlm.nih.gov/pubmed/34262037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24632-5
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